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HF4577 • 2026

Psilocybin therapeutic use program established; protections for registered patients, registered suppliers, registered facilitators, and health care practitioners established; civil actions authorized; advisory committee established; and money appropriated.

Psilocybin therapeutic use program established; protections for registered patients, registered suppliers, registered facilitators, and health care practitioners established; civil actions authorized; advisory committee established; and money appropriated.

Passed Legislature

This bill passed both chambers and reached final enrollment, even if later executive action is not shown here.

Sponsor
Rymer, Smith, West, Gordon, Bliss
Last action
2026-04-09
Official status
Motion to recall and re-refer, motion prevailed Veterans and Military Affairs Division
Effective date
Not listed

Plain English Breakdown

The plain English breakdown is still being put together. The official documents below are already here.

Bill History

  1. 2026-04-09 House

    Motion to recall and re-refer, motion prevailed Veterans and Military Affairs Division

  2. 2026-03-23 House

    Introduction and first reading, referred to Health Finance and Policy

Official Summary Text

Psilocybin therapeutic use program established; protections for registered patients, registered suppliers, registered facilitators, and health care practitioners established; civil actions authorized; advisory committee established; and money appropriated.

Current Bill Text

Read the full stored bill text
A bill for an act

relating to health; establishing a psilocybin therapeutic use program; establishing

protections for registered patients, registered suppliers, registered facilitators, and

health care practitioners; authorizing rulemaking; authorizing civil actions;

establishing fees; classifying data; establishing an advisory committee; providing

criminal penalties; appropriating money; amending Minnesota Statutes 2024,

section 152.02, subdivisions 2, 5; proposing coding for new law in Minnesota

Statutes, chapter 152.

BE IT ENACTED BY THE LEGISLATURE OF THE STATE OF MINNESOTA:

ARTICLE 1

THERAPEUTIC USE OF PSILOCYBIN

Section 1.
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PURPOSE.
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The purpose of this act is to establish a legal, regulated framework for the therapeutic

use of psilocybin by individuals who are 21 years of age or older with a licensed facilitator,

have been diagnosed with a qualifying medical condition, and meet the other requirements

for enrollment in the program.

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Sec. 2.

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[152.40] DEFINITIONS.

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Subdivision 1.

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Application.

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For purposes of sections 152.40 to 152.53, the following

terms have the meanings given.

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Subd. 2.

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Administration session.

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"Administration session" means a session supervised

by a registered facilitator during which a registered patient consumes and experiences the

effects of psilocybin.

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Subd. 3.

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Commissioner.

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"Commissioner" means the commissioner of health.

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Subd. 4.

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Health care practitioner.

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"Health care practitioner" means a Minnesota-licensed

physician.

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Subd. 5.

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Integration session.

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"Integration session" means a meeting between a registered

patient and a registered facilitator that occurs after the completion of an administration

session.

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Subd. 6.

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Preparation session.

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"Preparation session" means a meeting between a

registered patient and a registered facilitator that occurs before an administration session.

Preparation session does not mean an initial consultation between a registered patient and

a registered facilitator regarding psilocybin use, an inquiry from a registered patient to a

registered facilitator regarding psilocybin use, or a registered facilitator's response to a

registered patient's inquiry regarding psilocybin use.

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Subd. 7.

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Program.

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"Program" means the psilocybin therapeutic use program established

in sections 152.40 to 152.53.

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Subd. 8.

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Program research institution.

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"Program research institution" means a

Minnesota nonprofit or academic institution that advises and assists with program data

collection for public health monitoring, training, continuing education, and ethical oversight

requirements.

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Subd. 9.

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Psilocybin.

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"Psilocybin" means any mushroom in raw, dried, or prepared form

that contains the psychoactive compound psilocybin or its metabolite, psilocin.

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Subd. 10.

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Psychedelic Medicine Advisory Committee or advisory

committee.

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"Psychedelic Medicine Advisory Committee" or "advisory committee" means

the advisory committee established in section 152.53.

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Subd. 11.

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Qualifying medical condition.

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"Qualifying medical condition" means a

medical condition designated by the commissioner for which psilocybin shows evidence

for an appropriate therapeutic use, including but not limited to post-traumatic stress disorder,

depression, substance use disorders, anxiety, and chronic pain.

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Subd. 12.

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Registered facilitator.

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"Registered facilitator" means an individual registered

with the commissioner to provide services in preparation sessions and integration sessions

and to supervise administration sessions.

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Subd. 13.

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Registered patient.

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"Registered patient" means a Minnesota resident certified

by a health care practitioner as having a qualifying medical condition and enrolled in the

psilocybin therapeutic use program.

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Subd. 14.

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Registered supplier.

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"Registered supplier" means an individual or entity

licensed by the state to cultivate psilocybin for facilitated use in administration sessions.

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Subd. 15.

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Testing facility.

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"Testing facility" means a Minnesota entity certified by the

state to test the quality and dose of psilocybin to be used for treatment sessions.

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Subd. 16.

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Treatment facility.

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"Treatment facility" means a Minnesota health clinic or

center that has been licensed by the state with appropriately trained staff and safety equipment

for facilitated sessions. For accommodations for homebound patients, treatment facilities

can be at the patient's home with a registered facilitator and appropriate safety equipment

provided by the registered facilitator.

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Sec. 3.

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[152.41] PSILOCYBIN THERAPEUTIC USE PROGRAM.

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Subdivision 1.

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Establishment.

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The commissioner of health must establish and administer

a psilocybin therapeutic use program according to sections 152.40 to 152.53 in which

individuals 21 years of age or older who have a qualifying medical condition and meet the

other eligibility requirements may enroll in the program and are able to access and use

psilocybin with a registered facilitator at a treatment facility.

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Subd. 2.

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Rulemaking.

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(a) The commissioner must adopt rules to govern the operation

of the program. The rules must at least:

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(1) specify the qualifying medical conditions that an individual must be diagnosed with

in order to enroll in the program, based on emerging evidence from scientific research and

clinical trials evaluated in the psychedelic medicine task force legislative report, including

but not limited to post-traumatic stress disorder, depression, substance use disorders, anxiety,

chronic pain, and other conditions where scientific evidence shows there may be therapeutic

benefit;

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(2) specify testing standards in collaboration with the program research institution for

psilocybin mushrooms to ensure safety, appropriate dosing for treatment sessions, and

preventing diversion;

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(3) establish a standardized questionnaire in collaboration with the program research

institution for use by health care practitioners to conduct health screenings of individuals

seeking to enroll in the program;

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(4) establish a standardized formal risk assessment tool in collaboration with program

research for use by health care practitioners to evaluate identified contraindications in

individuals seeking to enroll in the program;

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(5) establish qualifications in collaboration with the program research institution to

register with the commissioner as a facilitator, including any additional subjects for which

individuals must demonstrate competency and specify how individuals must demonstrate

competency in the required subjects; and

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(6) establish qualifications to register with the commissioner as a cultivator in

collaboration with the program research institution, including any additional subjects for

which individuals must demonstrate competency in the required subjects and standards for

cultivation. Cultivators must work with testing facilities to ensure appropriate quality and

dosing of psilocybin before releasing psilocybin to registered facilitators and patients for

treatment.

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(b) The commissioner must consult with the advisory committee and the program research

institution in adopting rules under this subdivision.

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(c) Rules for which notice is published in the State Register before July 1, 2027, may

be adopted using the expedited rulemaking process in section 14.389. The notice of the

proposed rule for the requirements in paragraph (a) must be published in the State Register

no later than January 1, 2027.

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Subd. 3.

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Evaluation and research.

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(a) The commissioner must collect from registered

patients de-identified data on: (1) the frequency with which registered patients use psilocybin

in administration sessions; (2) the qualifying medical conditions for which psilocybin is

used; (3) the outcomes from psilocybin use experienced by registered patients; (4) adverse

effects of psilocybin use experienced by registered patients; and (5) any changes to utilization

by other health care, social services, or government-funded programs. Registered patients

and registered facilitators must provide data to the commissioner in a form and manner

specified by the commissioner. The commissioner must use data collected under this

paragraph to evaluate the program and, in consultation with the advisory committee and in

collaboration with the program research institution, develop recommendations to improve

the program. A program research institution may consult and partner with federal health

and research institutions.

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(b) The commissioner may support research that investigates novel therapeutic uses of

psilocybin and psilocin. In determining whether to support research initiatives, the

commissioner must consider the recommendations of the task force authorized under Laws

2023, chapter 70, article 4, section 99.

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Subd. 4.

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Interagency agreement with office of cannabis management.

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The

commissioner must enter into an interagency agreement with the commissioner of the Office

of Cannabis Management for administration of the psilocybin therapeutic use program. The

commissioner of the Office of Cannabis Management must have oversight over the following

program functions:

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(1) registered patient registries;

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(2) registered facilitator licensing; and

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(3) cultivation and testing of mushrooms in raw, dried, or prepared form that contain

the psychoactive compound psilocybin or its metabolite, psilocin.

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Sec. 4.

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[152.42] ELIGIBILITY AND ENROLLMENT IN PROGRAM.

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Subdivision 1.

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Registration system.

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The commissioner must administer a secure

registration system to track patients enrolled in the program while protecting patients'

privacy.

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Subd. 2.

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Eligibility for enrollment.

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(a) To enroll in the program, an individual must:

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(1) be 21 years of age or older;

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(2) submit to the commissioner a written certification from a health care practitioner

dated within 90 days of submission and verifying the individual's diagnosis with a qualifying

medical condition;

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(3) submit to the commissioner a written certification or certifications from one or more

health care practitioners dated within 90 days of submission and verifying that either:

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(i) the detailed health screening conducted according to subdivision 3 did not identify

contraindications to the individual's use of psilocybin; or

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(ii) the detailed health screening identified contraindications to the individual's use of

psilocybin, but a health care practitioner conducted a further evaluation using a formal risk

assessment tool and determined that the individual's identified contraindications should not

preclude the individual from using psilocybin; and

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(4) submit an application to the commissioner in a form and manner specified by the

commissioner.

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(b) Individuals may apply for enrollment in the program beginning January 1, 2027.

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Subd. 3.

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Health screening; evaluation.

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An individual who wishes to enroll in the

program must have a detailed health screening performed by a health care practitioner to

identify whether the individual has a qualifying medical condition and if the individual has

any significant physical or mental health conditions or medications that are contraindications

to the use of psilocybin. Contraindicated conditions may include but are not limited to

cardiovascular disease, psychosis, and bipolar disorders. Contraindicated medications include

but are not limited to lithium, monoamine oxidase inhibitors (MAOIs), tramadol, and

amphetamine stimulants. If the health care practitioner determines in the screening that the

individual has one or more contraindications to the use of psilocybin, the individual must

have the contraindication further evaluated by a health care practitioner using a formal risk

assessment tool. An individual who has an additional evaluation performed may proceed

with an application under subdivision 2 only if the health care practitioner performing the

additional evaluation determines that the individual's identified contraindications should

not preclude the individual from using psilocybin.

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Subd. 4.

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Informed consent.

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Upon receiving the individual's complete application and

certifications required under subdivision 2, the commissioner must provide the individual

with information on the nature of psilocybin use for therapeutic purposes, potential adverse

effects of psilocybin use, and possible interactions between psilocybin and other commonly

used drugs, along with a document, to be signed and returned by the individual, that the

individual has read and understood the information provided and wishes to enroll in the

program. An individual who wishes to proceed with the individual's application must sign

and date the informed consent form and return the form to the commissioner.

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Subd. 5.

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Enrollment.

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The commissioner must approve or deny the individual's application

within 60 days after receiving the individual's informed consent form under subdivision 4.

Upon approval of an individual's application and receipt of the enrollment fee required

under section 152.52, the commissioner must register the individual in the program and

issue the individual a card that permits the registered patient to access psilocybin with a

registered facilitator at a treatment facility.

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Subd. 6.

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Renewal.

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(a) A registered patient's registration is valid for 12 months from the

date of issuance. A registered patient who wishes to renew the registration must submit, at

least 60 days before the registration expires: (1) an application for registration renewal; (2)

written certifications that meet the requirements in subdivision 2, paragraph (a), clauses (2)

and (3); and (3) the fee required under section 152.52. The commissioner must approve or

deny a registered patient's renewal application within 60 days after receiving the complete

application and written certifications.

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(b) A registered patient whose registration has been expired for less than 31 days may

renew the registration under paragraph (a). A registered patient whose registration has been

expired for 31 or more days must apply for enrollment according to subdivision 2.

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Subd. 7.

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Permitted acts.

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(a) Subject to section 152.46, a registered patient is permitted

to:

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(1) designate a registered facilitator; and

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(2) consume the recommended amount of psilocybin at a treatment center with an

approved facilitator according to the recommended dosing limit.

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(b) Subject to section 152.46, a registered supplier and testing facility registered with

the commissioner is permitted to cultivate and possess psilocybin, provided the cultivation

and testing is performed according to section 152.43 and the total amount possessed does

not exceed the limit designated by the program.

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(c) Subject to section 152.46, a registered facilitator is permitted, according to section

152.44, to obtain psilocybin from a registered supplier, transport psilocybin to the treatment

center, provide services to registered patients in preparation sessions and integration sessions,

and administer psilocybin and supervise administration sessions of registered patients.

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(d) No civil or criminal penalty shall be imposed on:

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(1) a registered patient solely for engaging in an act listed in paragraph (a);

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(2) a registered cultivator and testing facility solely for engaging in an act listed in

paragraph (b); or

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(3) a registered facilitator solely for engaging in an act listed in paragraph (c).

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Subd. 8.

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Program initiation.

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The commissioner must approve an initial program

structured to include:

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(1) between 20 to 50 registered facilitators with experience conducting clinical trials

with psilocybin or administering ketamine-assisted therapy;

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(2) at least three testing facilities; and

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(3) no more than 1,000 patients with qualifying medical conditions into the program

during the first three years.

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Subd. 9.

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Program evaluation.

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The commissioner, in consultation with the advisory

committee and the program research institution, must evaluate the program at the end of

the three-year period.

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Sec. 5.

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[152.43] CULTIVATION.

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Subdivision 1.

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Cultivation authorized.

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(a) A registered patient and registered facilitator

may compensate a registered supplier who cultivates psilocybin for the program at a

registered facility. Compensating a registered supplier for cultivation under this subdivision

does not constitute the sale or commercial distribution of psilocybin.

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(b) Before cultivating psilocybin for the program, a registered supplier must register

with the commissioner.

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(c) A registered supplier must:

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(1) cultivate psilocybin only for approved treatment facilities, registered facilitators, and

registered patients in an amount that does not exceed the cultivation limit as established by

the commissioner of health; and

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(2) not cultivate psilocybin in an amount that exceeds the cultivation limit provided

under the registered supplier's license as designated by the commissioner.

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Subd. 2.

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Secure location.

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Cultivation by a licensed cultivator must take place at an

approved location in an enclosed and locked space that is not accessible to the public or to

individuals under 21 years of age and contains on-site testing facilities for quality and

potency testing.

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Sec. 6.

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[152.44] LOCATION AND FACILITATOR; ADMINISTRATION SESSIONS.

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Subdivision 1.

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Location.

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A registered patient may use psilocybin in an administration

session only at:

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(1) an approved private residence, including the curtilage or yard of the residence, unless

the property owner prohibits the use of psilocybin on the property; or

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(2) a licensed treatment facility, unless the property owner prohibits the use of psilocybin

on the property.

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Subd. 2.

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Registered facilitator.

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A registered facilitator must be physically present with

a registered patient during an administration session to supervise the registered patient's use

of psilocybin and to contact emergency services if necessary during the administration

session. As a condition of supervising an administration session for a registered patient, a

registered facilitator may require the registered patient to also participate in a preparation

session and an integration session with the registered facilitator. A registered facilitator may

charge a reasonable fee for the registered facilitator's services.

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Subd. 3.

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Informed consent.

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(a) Before a registered facilitator supervises a registered

patient's administration session, the registered facilitator must provide the registered patient

with information on the nature of psilocybin use for therapeutic purposes, what to expect

in an administration session, potential adverse effects of psilocybin use, and possible

interactions between psilocybin and other commonly used drugs. Registered patients will

also be allowed to opt in for consent to data collection to be used for program monitoring.

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(b) A registered patient who wishes to proceed with an administration session must sign

and date a document stating that the patient has been informed of and understands the

information provided in paragraph (a). A registered facilitator must maintain a signed

informed consent document for two years after receipt.

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Subd. 4.

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Chain of custody for psilocybin and psilocin.

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Before a registered patient's

administration session, a registered facilitator or registered patient must procure the

recommended dose of psilocybin from a registered supplier. At the time of exchange between

a registered supplier and a registered facilitator or registered patient, both the registered

supplier and the registered facilitator or the registered patient must attest to the exchange

on a form and in a manner specified by the commissioner, which must include, at a minimum,

the specific amount of psilocybin exchanged. Before an administration session, a registered

facilitator and registered patient must attest to the specific dose amount of psilocybin that

will be used in the treatment session in a form and manner specified by the commissioner.

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Sec. 7.

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[152.45] REGISTERED FACILITATOR.

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Subdivision 1.

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Registration required; qualifications.

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An individual must register with

the commissioner as a facilitator in order to supervise administration sessions for registered

patients and to provide registered patients with services in preparation sessions and integration

sessions. To register as a facilitator, an individual must:

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(1) be 21 years of age or older;

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(2) possess a license as a mental health professional as defined in section 245I.02,

subdivision 27; and

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(3) demonstrate competency, in a manner determined by the commissioner in

collaboration with the program research institution on: (i) facilitator ethics; (ii) the safe use

of psilocybin; (iii) the duties of a facilitator during preparation sessions, administration

sessions, and integration sessions; and (iv) other topics as determined by the commissioner

and the program research institution.

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An individual who holds a license, registration, or certification from a health-related licensing

board as defined in section 214.01, subdivision 2; from the Office of Emergency Medical

Services; or from the commissioner authorizing the individual to practice a health-related

occupation may also serve as a registered facilitator.

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Subd. 2.

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Application for registration; registration renewal.

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(a) An individual who

wishes to register as a facilitator must apply to the commissioner on a form and in a manner

specified by the commissioner.

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(b) A registration issued under this section is valid for 12 months from the date of

issuance. An individual who wishes to renew the individual's registration must apply for

registration renewal, on a form and in a manner specified by the commissioner, at least 60

days before the individual's registration expires. In evaluating an application for registration

renewal, the commissioner must consider any complaints reported to the commissioner

under subdivision 3 and may decline to renew an individual's registration if the commissioner

determines, based on complaints received or other evidence, that the individual did not

perform the duties of a facilitator in a safe or ethical manner. The commissioner must

approve or deny a registered facilitator's renewal application within 60 days after receiving

the facilitator's complete application.

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(c) A registered facilitator whose registration has been expired for less than 31 days may

renew the registration under paragraph (b). A registered facilitator whose registration has

been expired for 31 or more days must apply for registration according to paragraph (a),

except the commissioner must consider any complaints reported to the commissioner under

subdivision 3 and may decline to register the individual if the commissioner determines,

based on complaints received or other evidence, that the individual did not perform the

duties of a facilitator in a safe or ethical manner.

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(d) Individuals may apply for registration as a facilitator beginning October 1, 2026.

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Subd. 3.

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Complaints.

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The commissioner must accept complaints from registered patients

and other interested individuals regarding a registered facilitator's failure to supervise an

administration session in a safe or ethical manner or failure to provide services in a

preparation session or an integration session in a safe or ethical manner.

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Subd. 4.

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List of registered facilitators.

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The commissioner must post on the Department

of Health website the names and contact information of registered facilitators.

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Sec. 8.

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[152.46] LIMITATIONS.

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Nothing in sections 152.40 to 152.53 permits an individual to:

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(1) participate in the program if the individual is under 21 years of age;

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(2) sell psilocybin to an individual or engage in the distribution of psilocybin to anyone

not registered in the program;

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(3) establish treatment centers on the grounds of a public school, as defined in section

120A.05, subdivisions 9, 11, and 13, or a charter school governed by chapter 124E, including

all owned, rented, or leased facilities and all vehicles that a school district owns, leases,

rents, contracts for, or controls;

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(4) establish treatment centers in a state correctional facility;

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(5) if the individual is a registered facilitator, provide psilocybin to an individual who

is not a registered patient or supervise the administration session of an individual who is

not a registered patient; or

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(6) if the individual is a registered supplier, cultivate psilocybin not intended to be used

in the program for registered patients.

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Sec. 9.

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[152.47] CRIMINAL AND CIVIL PROTECTIONS.

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Subdivision 1.

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Forfeiture.

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Psilocybin cultivated or obtained under sections 152.40 to

152.53 and associated property are not subject to forfeiture under sections 609.531 to

609.5316.

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Subd. 2.

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Protections for public employees.

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Notwithstanding any law to the contrary,

the commissioner, the governor of Minnesota, or an employee of any state agency may not

be held civilly or criminally liable for any injury, loss of property, personal injury, or death

caused by any act or omission while acting within the scope of their office or employment

under sections 152.40 to 152.53.

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Subd. 3.

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Search warrant.

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Federal, state, and local law enforcement authorities are

prohibited from accessing the patient registry under sections 152.40 to 152.53 except when

acting pursuant to a valid search warrant.

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Subd. 4.

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Evidence in criminal proceeding.

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No information contained in a report,

document, or registry or obtained from a patient under sections 152.40 to 152.53 may be

admitted as evidence in a criminal proceeding unless independently obtained or in connection

with a proceeding involving a violation of sections 152.40 to 152.53. Any person who

violates this subdivision is guilty of a gross misdemeanor.

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Subd. 5.

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Possession of registry card or application.

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The possession of a registry card

or application for enrollment in the program by an individual entitled to possess a registry

card or apply for enrollment in the program does not constitute probable cause or reasonable

suspicion and shall not be used to support a search of the person or property of the individual

possessing the registry card or application, or otherwise subject the person or property of

the individual to inspection by any governmental agency.

new text end

new text begin

Subd. 6.

new text end

new text begin

Employment.

new text end

new text begin

An employer must not discriminate against a registered patient,

registered supplier, or registered facilitator in hiring, termination, or any term or condition

of employment or otherwise penalize a registered patient, registered supplier, or registered

facilitator based on the lawful cultivation, possession, transportation, provision of services

in preparation sessions or integration sessions, supervision of administration sessions, or

use of psilocybin under sections 152.40 to 152.53, unless:

new text end

new text begin

(1) the employer's failure to act would violate federal law or regulations or would cause

the employer to lose a monetary or licensing-related benefit under federal law or regulations;

or

new text end

new text begin

(2) the registered patient's use of psilocybin directly impacts the registered patient's job

performance or safety requirements of the registered patient's job position.

new text end

new text begin

Subd. 7.

new text end

new text begin

Housing.

new text end

new text begin

No landlord may refuse to lease to or evict a registered patient,

registered supplier, or registered facilitator solely for lawfully engaging in the psilocybin

program under sections 152.40 to 152.53, unless the landlord's failure to do so would violate

federal law or regulations or would cause the landlord to lose a monetary or licensing-related

benefit under federal law or regulations.

new text end

new text begin

Subd. 8.

new text end

new text begin

Education.

new text end

new text begin

No school may refuse to enroll a registered patient, registered

supplier, or registered facilitator solely for lawfully engaging with their respective treatment

or duties for the psilocybin program under sections 152.40 to 152.53, unless the school's

failure to do so would violate federal law or regulations or would cause the school to lose

a monetary or licensing-related benefit under federal law or regulations.

new text end

new text begin

Subd. 9.

new text end

new text begin

Custody; visitation; parenting time.

new text end

new text begin

A registered patient, registered supplier,

or registered facilitator must not be denied custody of a minor child or visitation rights or

parenting time with a minor child based solely on the registered patient's, registered supplier's,

or registered facilitator's lawful cultivation, possession, transportation, provision of services

in preparation sessions or integration sessions, supervision of administration sessions, or

use of psilocybin under sections 152.40 to 152.53, unless a registered patient's designated

behavior creates an unreasonable danger to the safety of the minor as demonstrated by clear

and convincing evidence.

new text end

new text begin

Subd. 10.

new text end

new text begin

Action for damages.

new text end

new text begin

In addition to any other remedy provided by law, a

registered patient, registered supplier, or registered facilitator who is injured by a violation

of subdivision 6, 7, 8, or 9 may bring an action for damages against a person who violates

subdivision 6, 7, 8, or 9. A person who violates subdivision 6, 7, 8, or 9 is liable to the

registered patient, registered supplier, or registered facilitator injured by the violation for

the greater of the registered patient's, registered supplier's, or registered facilitator's actual

damages or a civil penalty of $100, plus reasonable attorney fees.

new text end

Sec. 10.

new text begin

[152.48] VIOLATIONS.

new text end

new text begin

Subdivision 1.

new text end

new text begin

Diversion by registered patient, registered supplier, or registered

facilitator.

new text end

new text begin

In addition to any other applicable penalty in law, a registered patient, registered

supplier, or registered facilitator who intentionally sells or otherwise transfers psilocybin

to a person other than a registered patient is guilty of a felony punishable by imprisonment

for not more than two years or by payment of a fine of not more than $3,000, or both.

new text end

new text begin

Subd. 2.

new text end

new text begin

False statement.

new text end

new text begin

An individual who intentionally makes a false statement to

a law enforcement official about any fact or circumstance relating to the therapeutic use of

psilocybin to avoid arrest or prosecution is guilty of a misdemeanor punishable by

imprisonment for not more than 90 days or by payment of a fine of not more than $1,000,

or both. The penalty is in addition to any other penalties that may apply for making a false

statement or for the possession, cultivation, or sale of psilocybin not protected by sections

152.40 to 152.53. If a person convicted of violating this subdivision is a registered patient,

registered supplier, or registered facilitator, the person is disqualified from further

participation under the program.

new text end

Sec. 11.

new text begin

[152.49] PROTECTIONS FOR HEALTH CARE PRACTITIONERS AND

REGISTERED FACILITATORS.

new text end

new text begin

Subdivision 1.

new text end

new text begin

Health care practitioners.

new text end

new text begin

The Board of Medical Practice or Board of

Nursing must not impose civil or disciplinary penalties on, or limit or condition the practice

of, a health care practitioner licensed by the Board of Medical Practice or Board of Nursing

solely for certifying that an individual has a diagnosis of a qualifying medical condition

under section 152.42, subdivision 2, or performing health screenings or additional evaluations

under section 152.42, subdivision 3.

new text end

new text begin

Subd. 2.

new text end

new text begin

Registered facilitators.

new text end

new text begin

(a) A health-related licensing board, the Office of

Emergency Medical Services, or the commissioner must not impose civil or disciplinary

penalties on, or limit or condition the practice of, a registered facilitator who also holds a

license, registration, or certification from the health-related licensing board, the Office of

Emergency Medical Services, or the commissioner solely for obtaining and transporting

psilocybin for registered patients, providing services to registered patients in preparation

sessions and integration sessions, or administering psilocybin and supervising administration

sessions of registered patients, provided the services are provided or supervision is performed

under sections 152.40 to 152.53. No existing disciplinary procedures for complaints to the

health licensing boards shall be changed.

new text end

new text begin

(b) For the purposes of paragraph (a), the health-related licensing boards include the

Board of Medical Practice, Board of Nursing, Board of Psychology, Board of Social Work,

Board of Marriage and Family Therapy, and Board of Behavioral Health and Therapy.

new text end

Sec. 12.

new text begin

[152.50] PUBLIC EDUCATION AND HARM REDUCTION.

new text end

new text begin

Subdivision 1.

new text end

new text begin

Public education program.

new text end

new text begin

The commissioner, in collaboration with

the program research institution, must develop and implement a public education program

that makes information available to the public on the responsible use of psilocybin, potential

risks of using psilocybin, harm reduction strategies related to psilocybin use, and mental

health resources related to psilocybin use.

new text end

new text begin

Subd. 2.

new text end

new text begin

Training programs for first responders.

new text end

new text begin

The commissioner, in collaboration

with the program research institution, must develop and offer training programs for

emergency medical responders, ambulance service personnel, peace officers, and other first

responders on best practices for handling situations involving the use of psilocybin. The

training programs must be developed and offered in coordination with the Office of

Emergency Medical Services, the Peace Officer Standards and Training Board, the Minnesota

State Patrol, and local law enforcement agencies.

new text end

Sec. 13.

new text begin

[152.51] DATA PRACTICES; ACCESS TO AND USE OF DATA.

new text end

new text begin

(a) Except for the data specified in section 152.45, subdivision 4, data submitted to the

commissioner under section 152.42, 152.43, or 152.45:

new text end

new text begin

(1) is private data on individuals as defined in section 13.02, subdivision 12, or nonpublic

data as defined in section 13.02, subdivision 9; and

new text end

new text begin

(2) may only be used to comply with chapter 13, to comply with a request from the

legislative auditor or state auditors in the performance of official duties, and for purposes

specified in sections 152.40 to 152.53.

new text end

new text begin

(b) The data specified in paragraph (a) must not be combined or linked in any manner

with any other list, data set, or database and must not be shared with any federal agency,

federal department, or federal entity unless specifically ordered by a state or federal court,

or as part of a federally approved research project for monitoring of the program where a

certificate of confidentiality is obtained by a federal agency to protect the identities of the

program registrants.

new text end

Sec. 14.

new text begin

[152.52] FEES.

new text end

new text begin

(a) The commissioner must collect an annual fee of $....... from each patient whose

enrollment application or renewal application is approved by the commissioner.

new text end

new text begin

(b) Notwithstanding paragraph (a), if the patient provides evidence to the commissioner

of receiving Social Security disability insurance, Supplemental Security Income, or veterans

disability or railroad disability payments, or of being enrolled in medical assistance or

MinnesotaCare, the commissioner must collect an annual fee of $....... from the patient after

approving the patient's enrollment application or renewal application.

new text end

new text begin

(c) Fees collected under this section must be deposited in the state treasury and credited

to the state government special revenue fund. The commissioner may request appropriations

of fee revenue to distribute as grants to fund Minnesota-based research exploring the

effectiveness of psilocybin for additional conditions.

new text end

Sec. 15.

new text begin

[152.53] PSYCHEDELIC MEDICINE ADVISORY COMMITTEE.

new text end

new text begin

Subdivision 1.

new text end

new text begin

Establishment.

new text end

new text begin

The commissioner must establish a Psychedelic Medicine

Advisory Committee to advise the commissioner on the operation of the psilocybin

therapeutic use program under sections 152.40 to 152.53.

new text end

new text begin

Subd. 2.

new text end

new text begin

Membership.

new text end

new text begin

(a) The advisory committee shall consist of:

new text end

new text begin

(1) ... members with knowledge or expertise regarding the therapeutic use of psilocybin

and other psychedelic medicines, integration resources associated with the use of psilocybin,

and cultivation and testing of psilocybin. The commissioner must make recommendations

to the governor for members appointed under this clause, and the governor must appoint

members under this clause; and

new text end

new text begin

(2) one member representing Tribal Nations in the state, appointed by the Indian Affairs

Council.

new text end

new text begin

(b) Initial appointments must be made to the advisory committee by November 1, 2026.

new text end

new text begin

Subd. 3.

new text end

new text begin

Chairperson.

new text end

new text begin

Members of the advisory committee must elect a chairperson

from among the advisory committee's members.

new text end

new text begin

Subd. 4.

new text end

new text begin

Terms; compensation; removal of members.

new text end

new text begin

The advisory committee is

governed by section 15.059, except the advisory committee does not expire.

new text end

new text begin

Subd. 5.

new text end

new text begin

Meetings.

new text end

new text begin

The advisory committee must meet at least four times per year or at

the call of the chairperson. The initial meeting of the advisory committee must occur by

December 1, 2026, and must be called by the commissioner.

new text end

new text begin

Subd. 6.

new text end

new text begin

Staff support; office space; equipment.

new text end

new text begin

The commissioner must provide the

advisory committee with staff support, office space, and access to office equipment and

services.

new text end

Sec. 16.
new text begin
APPROPRIATION.
new text end

new text begin

$....... in fiscal year 2026 and $....... in fiscal year 2027 are appropriated from the general

fund to the commissioner of health for purposes of Minnesota Statutes, sections 152.40 to

152.53.

new text end

ARTICLE 2

SCHEDULING OF PSILOCYBIN

Section 1.

Minnesota Statutes 2024, section 152.02, subdivision 2, is amended to read:

Subd. 2.

Schedule I.

(a) Schedule I consists of the substances listed in this subdivision.

(b) Opiates. Unless specifically excepted or unless listed in another schedule, any of the

following substances, including their analogs, isomers, esters, ethers, salts, and salts of

isomers, esters, and ethers, whenever the existence of the analogs, isomers, esters, ethers,

and salts is possible:

(1) acetylmethadol;

(2) allylprodine;

(3) alphacetylmethadol (except levo-alphacetylmethadol, also known as levomethadyl

acetate);

(4) alphameprodine;

(5) alphamethadol;

(6) alpha-methylfentanyl benzethidine;

(7) betacetylmethadol;

(8) betameprodine;

(9) betamethadol;

(10) betaprodine;

(11) clonitazene;

(12) dextromoramide;

(13) diampromide;

(14) diethyliambutene;

(15) difenoxin;

(16) dimenoxadol;

(17) dimepheptanol;

(18) dimethyliambutene;

(19) dioxaphetyl butyrate;

(20) dipipanone;

(21) ethylmethylthiambutene;

(22) etonitazene;

(23) etoxeridine;

(24) furethidine;

(25) hydroxypethidine;

(26) ketobemidone;

(27) levomoramide;

(28) levophenacylmorphan;

(29) 3-methylfentanyl;

(30) acetyl-alpha-methylfentanyl;

(31) alpha-methylthiofentanyl;

(32) benzylfentanyl beta-hydroxyfentanyl;

(33) beta-hydroxy-3-methylfentanyl;

(34) 3-methylthiofentanyl;

(35) thenylfentanyl;

(36) thiofentanyl;

(37) para-fluorofentanyl;

(38) morpheridine;

(39) 1-methyl-4-phenyl-4-propionoxypiperidine;

(40) noracymethadol;

(41) norlevorphanol;

(42) normethadone;

(43) norpipanone;

(44) 1-(2-phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP);

(45) phenadoxone;

(46) phenampromide;

(47) phenomorphan;

(48) phenoperidine;

(49) piritramide;

(50) proheptazine;

(51) properidine;

(52) propiram;

(53) racemoramide;

(54) tilidine;

(55) trimeperidine;

(56) N-(1-Phenethylpiperidin-4-yl)-N-phenylacetamide (acetyl fentanyl);

(57) 3,4-dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-

methylbenzamide (U47700);

(58) N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide (furanylfentanyl);

(59) 4-(4-bromophenyl)-4-dimethylamino-1-phenethylcyclohexanol (bromadol);

(60) N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopropanecarboxamide (cyclopropyl

fentanyl);

(61) N-(1-phenethylpiperidin-4-yl)-N-phenylbutanamide) (butyryl fentanyl);

(62) 1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) (MT-45);

(63) N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopentanecarboxamide (cyclopentyl

fentanyl);

(64) N-(1-phenethylpiperidin-4-yl)-N-phenylisobutyramide (isobutyryl fentanyl);

(65) N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide (valeryl fentanyl);

(66) N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide

(para-chloroisobutyryl fentanyl);

(67) N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)butyramide (para-fluorobutyryl

fentanyl);

(68) N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl)butyramide

(para-methoxybutyryl fentanyl);

(69) N-(2-fluorophenyl)-2-methoxy-N-(1-phenethylpiperidin-4-yl)acetamide (ocfentanil);

(70) N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide (4-fluoroisobutyryl

fentanyl or para-fluoroisobutyryl fentanyl);

(71) N-(1-phenethylpiperidin-4-yl)-N-phenylacrylamide (acryl fentanyl or

acryloylfentanyl);

(72) 2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide (methoxyacetyl

fentanyl);

(73) N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)propionamide (ortho-fluorofentanyl

or 2-fluorofentanyl);

(74) N-(1-phenethylpiperidin-4-yl)-N-phenyltetrahydrofuran-2-carboxamide

(tetrahydrofuranyl fentanyl);

(75) Fentanyl-related substances, their isomers, esters, ethers, salts and salts of isomers,

esters and ethers, meaning any substance not otherwise listed under another federal

Administration Controlled Substance Code Number or not otherwise listed in this section,

and for which no exemption or approval is in effect under section 505 of the Federal Food,

Drug, and Cosmetic Act, United States Code, title 21, section 355, that is structurally related

to fentanyl by one or more of the following modifications:

(i) replacement of the phenyl portion of the phenethyl group by any monocycle, whether

or not further substituted in or on the monocycle;

(ii) substitution in or on the phenethyl group with alkyl, alkenyl, alkoxyl, hydroxyl, halo,

haloalkyl, amino, or nitro groups;

(iii) substitution in or on the piperidine ring with alkyl, alkenyl, alkoxyl, ester, ether,

hydroxyl, halo, haloalkyl, amino, or nitro groups;

(iv) replacement of the aniline ring with any aromatic monocycle whether or not further

substituted in or on the aromatic monocycle; or

(v) replacement of the N-propionyl group by another acyl group;

(76) 1-(1-(1-(4-bromophenyl)ethyl)piperidin-4-yl)-1,3-

dihydro-2H-benzo[d]imidazol-2-one (brorphine);

(77) 4'-methyl acetyl fentanyl;

(78) beta-hydroxythiofentanyl;

(79) beta-methyl fentanyl;

(80) beta'-phenyl fentanyl;

(81) crotonyl fentanyl ((E)-N-(1-phenethylpiperidin-4-yl)-N-phenylbut-2-enamide);

(82) cyclopropyl fentanyl

(N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopropanecarboxamide);

(83) fentanyl carbamate;

(84) isotonitazene (N,N-diethyl-2-(2-(4

isopropoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan-1-amine);

(85) para-fluoro furanyl fentanyl;

(86) para-methylfentanyl;

(87) phenyl fentanyl;

(88) ortho-fluoroacryl fentanyl;

(89) ortho-fluorobutyryl fentanyl;

(90) ortho-fluoroisobutyryl fentanyl;

(91) ortho-methyl acetylfentanyl;

(92) thiofuranyl fentanyl;

(93) metonitazene

(N,N-diethyl-2-(2-(4-methoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan-1-amine);

(94) metodesnitazene

(N,N-diethyl-2-(2-(4-methoxybenzyl)-1H-benzimidazol-1-yl)ethan-1-amine);

(95) etodesnitazene; etazene

(2-(2-(4-ethoxybenzyl)-1H-benzimidazol-1-yl)-N,N-diethylethan-1-amine);

(96) protonitazene

(N,N-diethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1-yl)ethan-1-amine);

(97) butonitazene

(2-(2-(4-butoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)-N,N-diethylethan-1-amine);

(98) flunitazene

(N,N-diethyl-2-(2-(4-fluorobenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan-1-amine); and

(99) N-pyrrolidino etonitazene; etonitazepyne

(2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole).

(c) Opium derivatives. Any of the following substances, their analogs, salts, isomers,

and salts of isomers, unless specifically excepted or unless listed in another schedule,

whenever the existence of the analogs, salts, isomers, and salts of isomers is possible:

(1) acetorphine;

(2) acetyldihydrocodeine;

(3) benzylmorphine;

(4) codeine methylbromide;

(5) codeine-n-oxide;

(6) cyprenorphine;

(7) desomorphine;

(8) dihydromorphine;

(9) drotebanol;

(10) etorphine;

(11) heroin;

(12) hydromorphinol;

(13) methyldesorphine;

(14) methyldihydromorphine;

(15) morphine methylbromide;

(16) morphine methylsulfonate;

(17) morphine-n-oxide;

(18) myrophine;

(19) nicocodeine;

(20) nicomorphine;

(21) normorphine;

(22) pholcodine; and

(23) thebacon.

(d) Hallucinogens. Any material, compound, mixture or preparation which contains any

quantity of the following substances, their analogs, salts, isomers (whether optical, positional,

or geometric), and salts of isomers, unless specifically excepted or unless listed in another

schedule, whenever the existence of the analogs, salts, isomers, and salts of isomers is

possible:

(1) methylenedioxy amphetamine;

(2) methylenedioxymethamphetamine;

(3) methylenedioxy-N-ethylamphetamine (MDEA);

(4) n-hydroxy-methylenedioxyamphetamine;

(5) 4-bromo-2,5-dimethoxyamphetamine (DOB);

(6) 2,5-dimethoxyamphetamine (2,5-DMA);

(7) 4-methoxyamphetamine;

(8) 5-methoxy-3, 4-methylenedioxyamphetamine;

(9) alpha-ethyltryptamine;

(10) bufotenine;

(11) diethyltryptamine;

(12) dimethyltryptamine;

(13) 3,4,5-trimethoxyamphetamine;

(14) 4-methyl-2, 5-dimethoxyamphetamine (DOM);

(15) ibogaine;

(16) lysergic acid diethylamide (LSD);

(17) mescaline;

(18) parahexyl;

(19) N-ethyl-3-piperidyl benzilate;

(20) N-methyl-3-piperidyl benzilate;

deleted text begin

(21) psilocybin;

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(22) psilocyn;

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(23)
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new text begin
(21)
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tenocyclidine (TPCP or TCP);

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(24)
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new text begin
(22)
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N-ethyl-1-phenyl-cyclohexylamine (PCE);

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(25)
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new text begin
(23)
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1-(1-phenylcyclohexyl) pyrrolidine (PCPy);

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(26)
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new text begin
(24)
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1-[1-(2-thienyl)cyclohexyl]-pyrrolidine (TCPy);

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(27)
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(25)
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4-chloro-2,5-dimethoxyamphetamine (DOC);

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(28)
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(26)
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4-ethyl-2,5-dimethoxyamphetamine (DOET);

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(29)
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(27)
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4-iodo-2,5-dimethoxyamphetamine (DOI);

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(30)
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new text begin
(28)
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4-bromo-2,5-dimethoxyphenethylamine (2C-B);

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(31)
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new text begin
(29)
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4-chloro-2,5-dimethoxyphenethylamine (2C-C);

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(32)
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new text begin
(30)
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4-methyl-2,5-dimethoxyphenethylamine (2C-D);

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(33)
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new text begin
(31)
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4-ethyl-2,5-dimethoxyphenethylamine (2C-E);

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(34)
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(32)
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4-iodo-2,5-dimethoxyphenethylamine (2C-I);

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(35)
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(33)
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4-propyl-2,5-dimethoxyphenethylamine (2C-P);

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(36)
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new text begin
(34)
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4-isopropylthio-2,5-dimethoxyphenethylamine (2C-T-4);

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(37)
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new text begin
(35)
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4-propylthio-2,5-dimethoxyphenethylamine (2C-T-7);

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(38)
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new text begin
(36)
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2-(8-bromo-2,3,6,7-tetrahydrofuro [2,3-f][1]benzofuran-4-yl)ethanamine

(2-CB-FLY);

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(39)
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new text begin
(37)
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bromo-benzodifuranyl-isopropylamine (Bromo-DragonFLY);

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(40)
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new text begin
(38)
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alpha-methyltryptamine (AMT);

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(41)
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new text begin
(39)
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N,N-diisopropyltryptamine (DiPT);

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(42)
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new text begin
(40)
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4-acetoxy-N,N-dimethyltryptamine (4-AcO-DMT);

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(43)
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new text begin
(41)
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4-acetoxy-N,N-diethyltryptamine (4-AcO-DET);

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(44)
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new text begin
(42)
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4-hydroxy-N-methyl-N-propyltryptamine (4-HO-MPT);

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(45)
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new text begin
(43)
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4-hydroxy-N,N-dipropyltryptamine (4-HO-DPT);

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(46)
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new text begin
(44)
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4-hydroxy-N,N-diallyltryptamine (4-HO-DALT);

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(47)
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(45)
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4-hydroxy-N,N-diisopropyltryptamine (4-HO-DiPT);

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(48)
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new text begin
(46)
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5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT);

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(49)
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new text begin
(47)
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5-methoxy-α-methyltryptamine (5-MeO-AMT);

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(50)
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(48)
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5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT);

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(51)
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(49)
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5-methylthio-N,N-dimethyltryptamine (5-MeS-DMT);

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(52)
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(50)
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5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT);

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(53)
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(51)
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5-methoxy-α-ethyltryptamine (5-MeO-AET);

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(54)
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(52)
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5-methoxy-N,N-dipropyltryptamine (5-MeO-DPT);

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(55)
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(53)
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5-methoxy-N,N-diethyltryptamine (5-MeO-DET);

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(56)
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(54)
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5-methoxy-N,N-diallyltryptamine (5-MeO-DALT);

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(57)
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(55)
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methoxetamine (MXE);

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(58)
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(56)
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5-iodo-2-aminoindane (5-IAI);

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(59)
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(57)
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5,6-methylenedioxy-2-aminoindane (MDAI);

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(60)
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(58)
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2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine

(25B-NBOMe);

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(61)
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(59)
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2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine

(25C-NBOMe);

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(62)
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(60)
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2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine

(25I-NBOMe);

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(63)
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(61)
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2-(2,5-Dimethoxyphenyl)ethanamine (2C-H);

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(64)
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(62)
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2-(4-Ethylthio-2,5-dimethoxyphenyl)ethanamine (2C-T-2);

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(65)
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(63)
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N,N-Dipropyltryptamine (DPT);

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(66)
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(64)
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3-[1-(Piperidin-1-yl)cyclohexyl]phenol (3-HO-PCP);

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(67)
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(65)
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N-ethyl-1-(3-methoxyphenyl)cyclohexanamine (3-MeO-PCE);

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(68)
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(66)
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4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (3-MeO-PCMo);

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(69)
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(67)
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1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine (methoxydine, 4-MeO-PCP);

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(70)
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(68)
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2-(2-Chlorophenyl)-2-(ethylamino)cyclohexan-1-one (N-Ethylnorketamine,

ethketamine, NENK);

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(69)
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methylenedioxy-N,N-dimethylamphetamine (MDDMA);

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(72)
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(70)
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3-(2-Ethyl(methyl)aminoethyl)-1H-indol-4-yl (4-AcO-MET); and

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(73)
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2-Phenyl-2-(methylamino)cyclohexanone (deschloroketamine).

(e) Peyote. All parts of the plant presently classified botanically as Lophophora williamsii

Lemaire, whether growing or not, the seeds thereof, any extract from any part of the plant,

and every compound, manufacture, salts, derivative, mixture, or preparation of the plant,

its seeds or extracts. The listing of peyote as a controlled substance in Schedule I does not

apply to the nondrug use of peyote in bona fide religious ceremonies of the American Indian

Church, and members of the American Indian Church are exempt from registration. Any

person who manufactures peyote for or distributes peyote to the American Indian Church,

however, is required to obtain federal registration annually and to comply with all other

requirements of law.

(f) Central nervous system depressants. Unless specifically excepted or unless listed in

another schedule, any material compound, mixture, or preparation which contains any

quantity of the following substances, their analogs, salts, isomers, and salts of isomers

whenever the existence of the analogs, salts, isomers, and salts of isomers is possible:

(1) mecloqualone;

(2) methaqualone;

(3) gamma-hydroxybutyric acid (GHB), including its esters and ethers;

(4) flunitrazepam;

(5) 2-(2-Methoxyphenyl)-2-(methylamino)cyclohexanone (2-MeO-2-deschloroketamine,

methoxyketamine);

(6) tianeptine;

(7) clonazolam;

(8) etizolam;

(9) flubromazolam; and

(10) flubromazepam.

(g) Stimulants. Unless specifically excepted or unless listed in another schedule, any

material compound, mixture, or preparation which contains any quantity of the following

substances, their analogs, salts, isomers, and salts of isomers whenever the existence of the

analogs, salts, isomers, and salts of isomers is possible:

(1) aminorex;

(2) cathinone;

(3) fenethylline;

(4) methcathinone;

(5) methylaminorex;

(6) N,N-dimethylamphetamine;

(7) N-benzylpiperazine (BZP);

(8) methylmethcathinone (mephedrone);

(9) 3,4-methylenedioxy-N-methylcathinone (methylone);

(10) methoxymethcathinone (methedrone);

(11) methylenedioxypyrovalerone (MDPV);

(12) 3-fluoro-N-methylcathinone (3-FMC);

(13) methylethcathinone (MEC);

(14) 1-benzofuran-6-ylpropan-2-amine (6-APB);

(15) dimethylmethcathinone (DMMC);

(16) fluoroamphetamine;

(17) fluoromethamphetamine;

(18) α-methylaminobutyrophenone (MABP or buphedrone);

(19) 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butan-1-one (butylone);

(20) 2-(methylamino)-1-(4-methylphenyl)butan-1-one (4-MEMABP or BZ-6378);

(21) 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl) pentan-1-one (naphthylpyrovalerone or

naphyrone);

(22) (alpha-pyrrolidinopentiophenone (alpha-PVP);

(23) (RS)-1-(4-methylphenyl)-2-(1-pyrrolidinyl)-1-hexanone (4-Me-PHP or MPHP);

(24) 2-(1-pyrrolidinyl)-hexanophenone (Alpha-PHP);

(25) 4-methyl-N-ethylcathinone (4-MEC);

(26) 4-methyl-alpha-pyrrolidinopropiophenone (4-MePPP);

(27) 2-(methylamino)-1-phenylpentan-1-one (pentedrone);

(28) 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one (pentylone);

(29) 4-fluoro-N-methylcathinone (4-FMC);

(30) 3,4-methylenedioxy-N-ethylcathinone (ethylone);

(31) alpha-pyrrolidinobutiophenone (α-PBP);

(32) 5-(2-Aminopropyl)-2,3-dihydrobenzofuran (5-APDB);

(33) 1-phenyl-2-(1-pyrrolidinyl)-1-heptanone (PV8);

(34) 6-(2-Aminopropyl)-2,3-dihydrobenzofuran (6-APDB);

(35) 4-methyl-alpha-ethylaminopentiophenone (4-MEAPP);

(36) 4'-chloro-alpha-pyrrolidinopropiophenone (4'-chloro-PPP);

(37) 1-(1,3-Benzodioxol-5-yl)-2-(dimethylamino)butan-1-one (dibutylone, bk-DMBDB);

(38) 1-(3-chlorophenyl) piperazine (meta-chlorophenylpiperazine or mCPP);

(39) 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)-pentan-1-one (N-ethylpentylone, ephylone);

(40) any other substance, except bupropion or compounds listed under a different

schedule, that is structurally derived from 2-aminopropan-1-one by substitution at the

1-position with either phenyl, naphthyl, or thiophene ring systems, whether or not the

compound is further modified in any of the following ways:

(i) by substitution in the ring system to any extent with alkyl, alkylenedioxy, alkoxy,

haloalkyl, hydroxyl, or halide substituents, whether or not further substituted in the ring

system by one or more other univalent substituents;

(ii) by substitution at the 3-position with an acyclic alkyl substituent;

(iii) by substitution at the 2-amino nitrogen atom with alkyl, dialkyl, benzyl, or

methoxybenzyl groups; or

(iv) by inclusion of the 2-amino nitrogen atom in a cyclic structure;

(41) 4,4'-dimethylaminorex (4,4'-DMAR;

4,5-dihydro-4-methyl-5-(4-methylphenyl)-2-oxazolamine);

(42) 4-chloro-alpha-pyrrolidinovalerophenone (4-chloro-A-PVP);

(43) para-methoxymethamphetamine (PMMA),

1-(4-methoxyphenyl)-N-methylpropan-2-amine; and

(44) N-ethylhexedrone.

(h) Synthetic cannabinoids, including the following substances:

(1) Naphthoylindoles, which are any compounds containing a 3-(1-napthoyl)indole

structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl,

alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or

2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any

extent and whether or not substituted in the naphthyl ring to any extent. Examples of

naphthoylindoles include, but are not limited to:

(i) 1-Pentyl-3-(1-naphthoyl)indole (JWH-018 and AM-678);

(ii) 1-Butyl-3-(1-naphthoyl)indole (JWH-073);

(iii) 1-Pentyl-3-(4-methoxy-1-naphthoyl)indole (JWH-081);

(iv) 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200);

(v) 1-Propyl-2-methyl-3-(1-naphthoyl)indole (JWH-015);

(vi) 1-Hexyl-3-(1-naphthoyl)indole (JWH-019);

(vii) 1-Pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122);

(viii) 1-Pentyl-3-(4-ethyl-1-naphthoyl)indole (JWH-210);

(ix) 1-Pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398);

(x) 1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM-2201).

(2) Napthylmethylindoles, which are any compounds containing a

1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the

indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl,

1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further

substituted in the indole ring to any extent and whether or not substituted in the naphthyl

ring to any extent. Examples of naphthylmethylindoles include, but are not limited to:

(i) 1-Pentyl-1H-indol-3-yl-(1-naphthyl)methane (JWH-175);

(ii) 1-Pentyl-1H-indol-3-yl-(4-methyl-1-naphthyl)methane (JWH-184).

(3) Naphthoylpyrroles, which are any compounds containing a 3-(1-naphthoyl)pyrrole

structure with substitution at the nitrogen atom of the pyrrole ring by an alkyl, haloalkyl,

alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or

2-(4-morpholinyl)ethyl group whether or not further substituted in the pyrrole ring to any

extent, whether or not substituted in the naphthyl ring to any extent. Examples of

naphthoylpyrroles include, but are not limited to,

(5-(2-fluorophenyl)-1-pentylpyrrol-3-yl)-naphthalen-1-ylmethanone (JWH-307).

(4) Naphthylmethylindenes, which are any compounds containing a naphthylideneindene

structure with substitution at the 3-position of the indene ring by an alkyl, haloalkyl, alkenyl,

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or

2-(4-morpholinyl)ethyl group whether or not further substituted in the indene ring to any

extent, whether or not substituted in the naphthyl ring to any extent. Examples of

naphthylemethylindenes include, but are not limited to,

E-1-[1-(1-naphthalenylmethylene)-1H-inden-3-yl]pentane (JWH-176).

(5) Phenylacetylindoles, which are any compounds containing a 3-phenylacetylindole

structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl,

alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or

2-(4-morpholinyl)ethyl group whether or not further substituted in the indole ring to any

extent, whether or not substituted in the phenyl ring to any extent. Examples of

phenylacetylindoles include, but are not limited to:

(i) 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole (RCS-8);

(ii) 1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250);

(iii) 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251);

(iv) 1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203).

(6) Cyclohexylphenols, which are compounds containing a

2-(3-hydroxycyclohexyl)phenol structure with substitution at the 5-position of the phenolic

ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl,

1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group whether or not substituted

in the cyclohexyl ring to any extent. Examples of cyclohexylphenols include, but are not

limited to:

(i) 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP 47,497);

(ii) 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (Cannabicyclohexanol

or CP 47,497 C8 homologue);

(iii) 5-(1,1-dimethylheptyl)-2-[(1R,2R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]

-phenol (CP 55,940).

(7) Benzoylindoles, which are any compounds containing a 3-(benzoyl)indole structure

with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl,

cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or

2-(4-morpholinyl)ethyl group whether or not further substituted in the indole ring to any

extent and whether or not substituted in the phenyl ring to any extent. Examples of

benzoylindoles include, but are not limited to:

(i) 1-Pentyl-3-(4-methoxybenzoyl)indole (RCS-4);

(ii) 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM-694);

(iii) (4-methoxyphenyl-[2-methyl-1-(2-(4-morpholinyl)ethyl)indol-3-yl]methanone

(WIN 48,098 or Pravadoline).

(8) Others specifically named:

(i) (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)

-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol (HU-210);

(ii) (6aS,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)

-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol (Dexanabinol or HU-211);

(iii) 2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]

-1,4-benzoxazin-6-yl-1-naphthalenylmethanone (WIN 55,212-2);

(iv) (1-pentylindol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone (UR-144);

(v) (1-(5-fluoropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone

(XLR-11);

(vi) 1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-1H-indazole-3-carboxamide

(AKB-48(APINACA));

(vii) N-((3s,5s,7s)-adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide

(5-Fluoro-AKB-48);

(viii) 1-pentyl-8-quinolinyl ester-1H-indole-3-carboxylic acid (PB-22);

(ix) 8-quinolinyl ester-1-(5-fluoropentyl)-1H-indole-3-carboxylic acid (5-Fluoro PB-22);

(x) N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-pentyl-1H-indazole-3-carboxamide

(AB-PINACA);

(xi) N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-

1H-indazole-3-carboxamide (AB-FUBINACA);

(xii) N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-(cyclohexylmethyl)-1H-

indazole-3-carboxamide(AB-CHMINACA);

(xiii) (S)-methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate

(5-fluoro-AMB);

(xiv) [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201);

(xv) (1-(5-fluoropentyl)-1H-benzo[d]imidazol-2-yl)(naphthalen-1-yl)methanone)

(FUBIMINA);

(xvi) (7-methoxy-1-(2-morpholinoethyl)-N-((1S,2S,4R)-1,3,3-trimethylbicyclo

[2.2.1]heptan-2-yl)-1H-indole-3-carboxamide (MN-25 or UR-12);

(xvii)

(S)-N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide

(5-fluoro-ABICA);

(xviii)

N-(1-amino-3-phenyl-1-oxopropan-2-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide;

(xix)

N-(1-amino-3-phenyl-1-oxopropan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide;

(xx) methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate;

(xxi) N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1(cyclohexylmethyl)

-1H-indazole-3-carboxamide (MAB-CHMINACA);

(xxii) N-(1-Amino-3,3-dimethyl-1-oxo-2-butanyl)-1-pentyl-1H-indazole-3-carboxamide

(ADB-PINACA);

(xxiii) methyl (1-(4-fluorobenzyl)-1H-indazole-3-carbonyl)-L-valinate (FUB-AMB);

(xxiv)

N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]-1-(cyclohexylmethyl)-1H-Indazole-

3-carboxamide (APP-CHMINACA);

(xxv) quinolin-8-yl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FUB-PB-22); and

(xxvi) methyl N-[1-(cyclohexylmethyl)-1H-indole-3-carbonyl]valinate (MMB-CHMICA).

(9) Additional substances specifically named:

(i) 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-B]pyridine-3-carboxamide

(5F-CUMYL-P7AICA);

(ii) 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide

(4-CN-Cumyl-Butinaca);

(iii) naphthalen-1-yl-1-(5-fluoropentyl)-1-H-indole-3-carboxylate (NM2201; CBL2201);

(iv)

N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide

(5F-ABPINACA);

(v) methyl-2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate

(MDMB CHMICA);

(vi) methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate

(5F-ADB; 5F-MDMB-PINACA);

(vii) N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)

1H-indazole-3-carboxamide (ADB-FUBINACA);

(viii) 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide;

(ix) (1-(4-fluorobenzyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone;

(x) methyl 2-(1-(4-fluorobenzyl)-1Hindazole-3-carboxamido)-3,3-dimethylbutanoate;

(xi) methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate;

(xii) ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate;

(xiii) methyl 2-(1-(4-fluorobenzyl)-1Hindazole-3-carboxamido)-3- methylbutanoate;

(xiv) N-(adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide; and

(xv) N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide.

(i) A controlled substance analog, to the extent that it is implicitly or explicitly intended

for human consumption.

Sec. 2.

Minnesota Statutes 2024, section 152.02, subdivision 5, is amended to read:

Subd. 5.

Schedule IV.

(a) Schedule IV consists of the substances listed in this subdivision.

(b) Narcotic drugs. Unless specifically excepted or unless listed in another schedule,

any material, compound, mixture, or preparation containing any of the following narcotic

drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities

as follows:

(1) not more than one milligram of difenoxin and not less than 25 micrograms of atropine

sulfate per dosage unit;

(2) dextropropoxyphene (Darvon and Darvocet);

(3) 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, its salts, optical and

geometric isomers, and salts of these isomers (including tramadol);

(4) eluxadoline;

(5) pentazocine; and

(6) butorphanol (including its optical isomers).

(c) Depressants. Unless specifically excepted or unless listed in another schedule, any

material, compound, mixture, or preparation containing any quantity of the following

substances, including its salts, isomers, and salts of isomers whenever the existence of the

salts, isomers, and salts of isomers is possible:

(1) alfaxalone (5α-pregnan-3α-ol-11,20-dione);

(2) alprazolam;

(3) barbital;

(4) bromazepam;

(5) camazepam;

(6) carisoprodol;

(7) chloral betaine;

(8) chloral hydrate;

(9) chlordiazepoxide;

(10) clobazam;

(11) clonazepam;

(12) clorazepate;

(13) clotiazepam;

(14) cloxazolam;

(15) delorazepam;

(16) diazepam;

(17) dichloralphenazone;

(18) estazolam;

(19) ethchlorvynol;

(20) ethinamate;

(21) ethyl loflazepate;

(22) fludiazepam;

(23) flurazepam;

(24) fospropofol;

(25) halazepam;

(26) haloxazolam;

(27) ketazolam;

(28) loprazolam;

(29) lorazepam;

(30) lormetazepam mebutamate;

(31) medazepam;

(32) meprobamate;

(33) methohexital;

(34) methylphenobarbital;

(35) midazolam;

(36) nimetazepam;

(37) nitrazepam;

(38) nordiazepam;

(39) oxazepam;

(40) oxazolam;

(41) paraldehyde;

(42) petrichloral;

(43) phenobarbital;

(44) pinazepam;

(45) prazepam;

(46) quazepam;

(47) suvorexant;

(48) temazepam;

(49) tetrazepam;

(50) triazolam;

(51) zaleplon;

(52) zolpidem;

(53) zopiclone;

(54) brexanolone (3α-hydroxy-5α-pregnan-20-one);

(55) lemborexant;

(56) remimazolam (4H-imidazol[1,2-a][1,4]benzodiazepine4-propionic acid).

(d) Any material, compound, mixture, or preparation which contains any quantity of the

following substance including its salts, isomers, and salts of such isomers, whenever the

existence of such salts, isomers, and salts of isomers is possible: fenfluramine.

(e) Stimulants. Unless specifically excepted or unless listed in another schedule, any

material, compound, mixture, or preparation which contains any quantity of the following

substances having a stimulant effect on the central nervous system, including its salts,

isomers, and salts of isomers:

(1) cathine (norpseudoephedrine);

(2) diethylpropion;

(3) fencamfamine;

(4) fenproporex;

(5) mazindol;

(6) mefenorex;

(7) modafinil;

(8) pemoline (including organometallic complexes and chelates thereof);

(9) phentermine;

(10) pipradol;

(11) sibutramine;

(12) SPA (1-dimethylamino-1,2-diphenylethane);

(13) serdexmethylphenidate;

(14) solriamfetol (2-amino-3-phenylpropyl car-bamate; benzenepropanol, beta-amino-,

carbamate (ester)).

(f) lorcaserin.

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(g) Hallucinogens. Any material, compound, mixture, or preparation that contains any

quantity of the following substances; the substances' analogs; salts; isomers, whether optical,

positional, or geometric; and salts of isomers, unless specifically excepted or unless listed

in another schedule, whenever the existence of the analogs, salts, isomers, and salts of

isomers is possible:

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(1) psilocybin; and

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(2) psilocin.

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