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PRINTER'S NO. 2527
THE GENERAL ASSEMBLY OF PENNSYLVANIA
HOUSE RESOLUTION
No. 358
Session of
2025
INTRODUCED BY SCOTT, DALEY, SANCHEZ, HOWARD, KENYATTA AND
GUENST, OCTOBER 24, 2025
REFERRED TO COMMITTEE ON HEALTH, OCTOBER 27, 2025
A RESOLUTION
Recognizing November 1, 2025, as "Tylenol Day" in Pennsylvania.
WHEREAS, In 1884, two German physicians prescribed
naphthalene to a patient they were treating for worms and a
fever; and
WHEREAS, The naphthalene did not relieve the patient's worms,
but it did reduce the patient's fever, an effect that was not
previously known; and
WHEREAS, The physicians learned that the pharmacy had made a
mistake and provided acetanilide, a compound isolated from coal
tar; and
WHEREAS, The physicians worked with a pharmaceutical firm to
investigate the effects of acetanilide and confirmed that it
reduced fever; and
WHEREAS, After acetanilide was marketed as Antifebrin, users
reported bluish skin after taking it; and
WHEREAS, The cause of the bluish skin was identified as
methemoglobinemia, a condition in which the oxygen transported
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by hemoglobin is impaired; and
WHEREAS, These findings led researchers to seek safer
alternatives by altering the molecular structure of compounds to
eliminate side effects; and
WHEREAS, In 1887, a German company known as Bayer modified
acetanilide to produce phenacetin, which did not cause
methemoglobinemia; and
WHEREAS, Later in 1887, a physician and a chemist worked
together to find another derivative of acetanilide, now known as
acetaminophen; and
WHEREAS, The founders of acetaminophen recommended an
extensive investigation into the medication before it became
available to the public; and
WHEREAS, The effectiveness and safety of acetaminophen as a
fever and pain reliever were not confirmed until 1949, based on
modern research techniques and clinical use in England; and
WHEREAS, Because phenacetin was linked to kidney problems and
aspirin to stomach problems, acetaminophen was promoted as the
safer medication; and
WHEREAS, In the late 1940s, McNeil Laboratories, a
Philadelphia family-owned business, began studying the safety
and efficacy of acetaminophen in hopes of marketing it for a
future product; and
WHEREAS, McNeil Laboratories began as a family-run pharmacy
and later expanded into the manufacturing of prescription
medicines; and
WHEREAS, In 1955, McNeil Laboratories introduced Tylenol
Elixir for Children after receiving approval by the United
States Food and Drug Administration (FDA); and
WHEREAS, Tylenol Elixir for Children was the first single-
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ingredient acetaminophen product on the market and was available
only by prescription; and
WHEREAS, In 1959, Johnson & Johnson acquired McNeil
Laboratories; and
WHEREAS, In 1959, Tylenol was approved for sale without a
prescription, leading to its availability over the counter the
following year; and
WHEREAS, Tylenol has become the best-known product of the
more than 600 products on the market that contain the active
ingredient acetaminophen; and
WHEREAS, Tylenol has more than two dozen products in various
forms, including liquids, dissolvable powders, chewable tablets,
caplets and capsules; and
WHEREAS, Each Tylenol product is formulated for different
symptoms, age groups and delivery methods; and
WHEREAS, Tylenol offers products for pain and fever relief,
as well as for arthritis, cold and flu symptoms, sinus relief
and sleep; and
WHEREAS, It is estimated that nearly 25% of adults in the
United States use a medication containing acetaminophen each
week; and
WHEREAS, Tylenol is the number one doctor-recommended pain
reliever brand; and
WHEREAS, The year 2025 commemorates the 70th anniversary of
Tylenol receiving FDA approval and being introduced by McNeil
Laboratories; therefore be it
RESOLVED, That the House of Representatives recognize
November 1, 2025, as "Tylenol Day" in Pennsylvania.
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